Antineutrophil cytoplasmic antibodies

From Citizendium
Revision as of 11:29, 3 October 2008 by imported>Robert Badgett (New page: {{subpages}} In medicine and rheumatology, '''antineutrophil cytoplasmic antibodies''' ('''ANCA''') are "Autoantibodies directed against cytoplasmic constituents o...)
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to navigation Jump to search
This article is developing and not approved.
Main Article
Discussion
Related Articles  [?]
Bibliography  [?]
External Links  [?]
Citable Version  [?]
 
This editable Main Article is under development and subject to a disclaimer.

In medicine and rheumatology, antineutrophil cytoplasmic antibodies (ANCA) are "Autoantibodies directed against cytoplasmic constituents of polymorphonuclear leukocytes and/or monocytes. They are used as specific markers for Wegener Granulomatosis and other diseases, though their pathophysiological role is not clear. ANCA are routinely detected by indirect immunofluorescence with three different patterns: c-ANCA (cytoplasmic), p-ANCA (perinuclear), and atypical ANCA."[1]

References