Glycosylated hemoglobin A

Glycosylated hemoglobin A, also referred to by it medically most important component Hb A1c, is blood test used to monitor the treatment of diabetes mellitus type 1 and diabetes mellitus type 2. Glycosylated hemoglobin A are "minor hemoglobin components of human erythrocytes designated A1a, A1b, and A1c. Hemoglobin A1c is most important since its sugar moiety is glucose covalently bound to the terminal amino acid of the beta chain. Since normal glycohemoglobin concentrations exclude marked blood glucose fluctuations over the preceding three to four weeks, the concentration of glycosylated hemoglobin A is a more reliable index of the blood sugar average over a long period of time."