Second-generation antidepressant

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Second-generation antidepressants are used to treat depression and are a "structurally and mechanistically diverse group of drugs that are not tricyclics or monoamine oxidase inhibitors. The most clinically important appear to act selectively on serotonergic systems, especially by inhibiting serotonin reuptake."[1]

Classification

Second-generation antidepressants are classified by the biogenic amine receptor that they affect.

Selective serotonin reuptake inhibitors(SSRI)

Serotonin 5-HT2–receptor agonist

Serotonin norepinephrine reuptake inhibitors (SNRI)

Norepinephrine uptake inhibitor

Dopamine reuptake inhibitor

References

  1. ↑ Anonymous (2024), Second-generation antidepressants (English). Medical Subject Headings. U.S. National Library of Medicine.
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