Aminostatic hypothesis

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In 1956, Mellinkoff proposed the aminostatic hypothesis, stimulated by the observation that when normal individuals ingest protein, appetite diminishes as the serum amino acid concentration rises and vice versa.[1]

References

  1. Mellinkoff SM et al. (1956) Relationship between serum amino acid concentration and fluctuations in appetite J Appl Physiol 8:535-8 PMID 13295170

Experimental Evidence