Zolpidem: Difference between revisions
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In [[pharmacology]], '''zolpidem''' is an agonist of the inhibitory [[neurotransmitter]] [[gamma-aminobutyric acid]] (GABA). Zolpidem's pharmacological action is in the category of [[sedative|hypnotics and sedatives]]. Zolpidem is one of the Z drugs ([[zopiclone]], [[eszopiclone]], zolpidem, and [[zaleplon]]). | In [[pharmacology]], '''zolpidem''' is an agonist of the inhibitory [[neurotransmitter]] [[gamma-aminobutyric acid]] (GABA). Zolpidem's pharmacological action is in the category of [[sedative|hypnotics and sedatives]]. Zolpidem is one of the Z drugs ([[zopiclone]], [[eszopiclone]], zolpidem, and [[zaleplon]]). | ||
==Efficacny== | |||
In [[geriatric]], the benefits of zolpidem to not clearly ex cede the [[drug toxicity]].<ref name="pmid16284208">{{cite journal| author=Glass J, Lanctôt KL, Herrmann N, Sproule BA, Busto UE| title=Sedative hypnotics in older people with insomnia: meta-analysis of risks and benefits. | journal=BMJ | year= 2005 | volume= 331 | issue= 7526 | pages= 1169 | pmid=16284208 | |||
| url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=clinical.uthscsa.edu/cite&email=badgett@uthscdsa.edu&retmode=ref&cmd=prlinks&id=16284208 | doi=10.1136/bmj.38623.768588.47 | pmc=PMC1285093 }} [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=clinical.uthscsa.edu/cite&email=badgett@uthscdsa.edu&retmode=ref&cmd=prlinks&id=16813362 Review in: ACP J Club. 2006 Jul-Aug;145(1):14] [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=clinical.uthscsa.edu/cite&email=badgett@uthscdsa.edu&retmode=ref&cmd=prlinks&id=17213123 Review in: Evid Based Med. 2006 Aug;11(4):110] [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=clinical.uthscsa.edu/cite&email=badgett@uthscdsa.edu&retmode=ref&cmd=prlinks&id=16865838 Review in: Evid Based Nurs. 2006 Jul;9(3):87] <!--Formatted by http://sumsearch.uthscsa.edu/cite/--></ref><ref name="pmid9417012">{{cite journal| author=Nowell PD, Mazumdar S, Buysse DJ, Dew MA, Reynolds CF, Kupfer DJ| title=Benzodiazepines and zolpidem for chronic insomnia: a meta-analysis of treatment efficacy. | journal=JAMA | year= 1997 Dec 24-31 | volume= 278 | issue= 24 | pages= 2170-7 | pmid=9417012 | |||
| url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=clinical.uthscsa.edu/cite&email=badgett@uthscdsa.edu&retmode=ref&cmd=prlinks&id=9417012 }} <!--Formatted by http://sumsearch.uthscsa.edu/cite/--></ref> | |||
== More Information== | == More Information== |
Revision as of 14:39, 1 December 2009
In pharmacology, zolpidem is an agonist of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA). Zolpidem's pharmacological action is in the category of hypnotics and sedatives. Zolpidem is one of the Z drugs (zopiclone, eszopiclone, zolpidem, and zaleplon).
Efficacny
In geriatric, the benefits of zolpidem to not clearly ex cede the drug toxicity.[1][2]
More Information
- The most up-to-date information about Zolpidem and other drugs can be found at the following sites.
- Zolpidem - FDA approved drug information (drug label) from DailyMed (U.S. National Library of Medicine).
- Zolpidem - Drug information for consumers from MedlinePlus (U.S. National Library of Medicine).
- Zolpidem - Detailed information from DrugBank.
References
- ↑ Glass J, Lanctôt KL, Herrmann N, Sproule BA, Busto UE (2005). "Sedative hypnotics in older people with insomnia: meta-analysis of risks and benefits.". BMJ 331 (7526): 1169. DOI:10.1136/bmj.38623.768588.47. PMID 16284208. PMC PMC1285093. Research Blogging. Review in: ACP J Club. 2006 Jul-Aug;145(1):14 Review in: Evid Based Med. 2006 Aug;11(4):110 Review in: Evid Based Nurs. 2006 Jul;9(3):87
- ↑ Nowell PD, Mazumdar S, Buysse DJ, Dew MA, Reynolds CF, Kupfer DJ (1997 Dec 24-31). "Benzodiazepines and zolpidem for chronic insomnia: a meta-analysis of treatment efficacy.". JAMA 278 (24): 2170-7. PMID 9417012.