Acebutolol: Difference between revisions
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imported>David E. Volk (New page: {{subpages}} {{Chem infobox |align=right |image=center|thumb|300px |width=300px |molname=acebutolol |synonyms= dl-acebutolol |molformula= C<sub>18</sub>H<sub>28</...) |
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'''Acebutolol''' is a cardioselective, [[beta-adrenergic antagonist]] (beta blocker) with relatively little effects, at low dosage, on bronchial receptors compared to other beta-blockers such as [[atenolol]] and [[propranolol]]. [[Epinephrine]] typically binds to these same receptors, subsequently raising heart rate and blood pressure, but this action is blocked when beta-blockers such as acebutolol bind to these receptors, thereby interferring with epinephrine binding. Blood pressure is also increased by the release of [[renin]], a [[hormone]] produced in the kidneys, which narrows blood vessels. By preventing renin release, acebutolol reduces blood pressure by a second mechanism.[http://www.drugbank.ca/drugs/DB01193 Acebutolol at DrugBank] | '''Acebutolol''' is a cardioselective, [[beta-adrenergic antagonist]] (beta blocker) with relatively little effects, at low dosage, on bronchial receptors compared to other beta-blockers such as [[atenolol]] and [[propranolol]]. [[Epinephrine]] typically binds to these same receptors, subsequently raising heart rate and blood pressure, but this action is blocked when beta-blockers such as acebutolol bind to these receptors, thereby interferring with epinephrine binding. Blood pressure is also increased by the release of [[renin]], a [[hormone]] produced in the kidneys, which narrows blood vessels. By preventing renin release, acebutolol reduces blood pressure by a second mechanism. <ref>[http://www.drugbank.ca/drugs/DB01193 Acebutolol at DrugBank]</ref> | ||
== References == | == References == | ||
<references/> | <references/> | ||
Revision as of 14:53, 4 July 2009
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| Uses: | hypertention;angina pectoris | ||||||
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Acebutolol is a cardioselective, beta-adrenergic antagonist (beta blocker) with relatively little effects, at low dosage, on bronchial receptors compared to other beta-blockers such as atenolol and propranolol. Epinephrine typically binds to these same receptors, subsequently raising heart rate and blood pressure, but this action is blocked when beta-blockers such as acebutolol bind to these receptors, thereby interferring with epinephrine binding. Blood pressure is also increased by the release of renin, a hormone produced in the kidneys, which narrows blood vessels. By preventing renin release, acebutolol reduces blood pressure by a second mechanism. [1]