Acebutolol: Difference between revisions
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'''Acebutolol''' is a cardioselective, [[beta-adrenergic antagonist]] (beta blocker) with relatively little effects, at low dosage, on bronchial receptors compared to other beta-blockers such as [[atenolol]] and [[propranolol]]. [[Epinephrine]] typically binds to these same receptors, subsequently raising heart rate and blood pressure, but this action is blocked when beta-blockers such as acebutolol bind to these receptors, thereby interfering with epinephrine binding. Blood pressure is also increased by the release of [[renin]], a [[hormone]] produced in the kidneys, which narrows blood vessels. By preventing renin release, acebutolol reduces blood pressure by a second mechanism. <ref>[http://www.drugbank.ca/drugs/DB01193 Acebutolol at DrugBank]</ref> | |||
'''Acebutolol''' is a cardioselective, [[beta-adrenergic antagonist]] (beta blocker) with relatively little effects, at low dosage, on bronchial receptors compared to other beta-blockers such as [[atenolol]] and [[propranolol]]. [[Epinephrine]] typically binds to these same receptors, subsequently raising heart rate and blood pressure, but this action is blocked when beta-blockers such as acebutolol bind to these receptors, thereby | |||
== References == | == References == | ||
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== General References == | == General References == | ||
{{CZMed}} | {{CZMed}} | ||
Revision as of 10:54, 21 September 2013
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| Uses: | hypertention;angina pectoris | ||||||
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Acebutolol is a cardioselective, beta-adrenergic antagonist (beta blocker) with relatively little effects, at low dosage, on bronchial receptors compared to other beta-blockers such as atenolol and propranolol. Epinephrine typically binds to these same receptors, subsequently raising heart rate and blood pressure, but this action is blocked when beta-blockers such as acebutolol bind to these receptors, thereby interfering with epinephrine binding. Blood pressure is also increased by the release of renin, a hormone produced in the kidneys, which narrows blood vessels. By preventing renin release, acebutolol reduces blood pressure by a second mechanism. [1]
References
General References
The most up-to-date information about Acebutolol and other drugs can be found at the following sites.
- Acebutolol - FDA approved drug information (drug label) from DailyMed (U.S. National Library of Medicine).
- Acebutolol - Drug information for consumers from MedlinePlus (U.S. National Library of Medicine).
- Acebutolol - Detailed information from DrugBank.