Vitamin E: Difference between revisions
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In [[biochemistry]], '''vitamin E''' is a "generic descriptor for all [[tocopherol]]s and [[tocotrienol]]s that exhibit [[alpha-tocopherol]] activity. by virtue of the phenolic hydrogen on the 2h-1-benzopyran-6-ol nucleus, these compounds exhibit varying degree of [[antioxidant]] activity, depending on the site and number of methyl groups and the type of [[isoprenoid]]s."<ref>{{MeSH}}</ref> | In [[biochemistry]], '''vitamin E''' is a "generic descriptor for all [[tocopherol]]s and [[tocotrienol]]s that exhibit [[alpha-tocopherol]] activity. by virtue of the phenolic hydrogen on the 2h-1-benzopyran-6-ol nucleus, these compounds exhibit varying degree of [[antioxidant]] activity, depending on the site and number of methyl groups and the type of [[isoprenoid]]s."<ref>{{MeSH}}</ref> | ||
In 2005, a [[meta-analysis]] concluded that Vitamin E supplementation may actually be harmful when used for the prevention of [[vascular disease]].<ref name="pmid15537682">{{cite journal |author=Miller ER, Pastor-Barriuso R, Dalal D, Riemersma RA, Appel LJ, Guallar E |title=Meta-analysis: high-dosage vitamin E supplementation may increase all-cause mortality |journal=Ann. Intern. Med. |volume=142 |issue=1 |pages=37–46 |year=2005 |month=January |pmid=15537682 |doi= |url= |issn=}}</ref> | |||
==References== | ==References== | ||
<references/> | <references/> |
Revision as of 09:56, 6 May 2010
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Nonfatal MI | |
---|---|
Vitamin E 800 IU/day | 2.0% (11/546) |
Vitamin E 400 IU/day | 0.6% (3/489) |
Placebo | 4.2% (41/967) |
In biochemistry, vitamin E is a "generic descriptor for all tocopherols and tocotrienols that exhibit alpha-tocopherol activity. by virtue of the phenolic hydrogen on the 2h-1-benzopyran-6-ol nucleus, these compounds exhibit varying degree of antioxidant activity, depending on the site and number of methyl groups and the type of isoprenoids."[2]
In 2005, a meta-analysis concluded that Vitamin E supplementation may actually be harmful when used for the prevention of vascular disease.[3]
References
- ↑ Stephens NG, Parsons A, Schofield PM, Kelly F, Cheeseman K, Mitchinson MJ (March 1996). "Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS)". Lancet 347 (9004): 781–6. DOI:10.1016/S0140-6736(96)90866-1. PMID 8622332. Research Blogging.
- ↑ Anonymous (2024), Vitamin E (English). Medical Subject Headings. U.S. National Library of Medicine.
- ↑ Miller ER, Pastor-Barriuso R, Dalal D, Riemersma RA, Appel LJ, Guallar E (January 2005). "Meta-analysis: high-dosage vitamin E supplementation may increase all-cause mortality". Ann. Intern. Med. 142 (1): 37–46. PMID 15537682. [e]