Spironolactone

(CC) Image: David E. Volk
Spironolactone, an aldosterone antagonist.

Spironolactone is an aldosterone antagonist used to treat edema associated with congestive heart failure, nephrotic syndrome or hepatic cirrhosis. Although it can also be used treat hirsutism and acne by effecting the endocrine system, such use can lead to adverse side effects. Its IUPAC name is S-[(7R,8R,9S,10R,13S,14S,17R)-10,13-dimethyl-3,5'-dioxospiro[2,6,7,8,9,11,12,14,15, 16-decahydro-1H-cyclopenta[a]phenanthrene-17,2'-oxolane]-7-yl] ethanethioate.

trade names

• Abbolactone
• Acelat
• Aldace
• Aldactazide
• Aldactide
• Aldactone
• Aldactone A
• Alderon
• Aldopur
• Almatol
• Altex
• Aquareduct
• Deverol
• Diatensec
• Dira
• Duraspiron
• Espironolactona [INN-Spanish]
• Euteberol
• Lacalmin
• Lacdene
• Laractone
• Melarcon
• Nefurofan
• Osyrol
• SNL
• Sagisal
• Sincomen
• Spiresis
• Spiretic
• Spiridon
• Spiro-Tablinen
• Spiroctan
• Spiroctanie
• Spiroderm
• Spirolactone
• Spirolakton
• Spirolang
• Spirolone
• Spirone
• Spironocompren
• Spironolactone A
• Spironolactone [BAN:INN:JAN]
• Spironolactonum [INN-Latin]
• Spironolattone [DCIT]
• Sprioderm
• Supra-puren
• Suracton
• Uractone
• Urusonin
• Verospiron
• Verospirone
• Verospirone Opianin
• Xenalon

External links

The most up-to-date information about Spironolactone and other drugs can be found at the following sites.

• Spironolactone - FDA approved drug information (drug label) from DailyMed (U.S. National Library of Medicine).
• Spironolactone - Drug information for consumers from MedlinePlus (U.S. National Library of Medicine).
• Spironolactone - Detailed information from DrugBank.