Pneumonia: Difference between revisions

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**arterial pH < 7.35 (2 points)
**arterial pH < 7.35 (2 points)


===Prognosis at the time of discharge===
Abnormal [[medical sign]]s at discharge are associated with higher mortality with 30 days.<ref name="pmid18490403">{{cite journal |author=Capelastegui A, España PP, Bilbao A, ''et al'' |title=Pneumonia: criteria for patient instability on hospital discharge |journal=Chest |volume=134 |issue=3 |pages=595–600 |year=2008 |month=September |pmid=18490403 |doi=10.1378/chest.07-3039 |url=http://www.chestjournal.org/cgi/pmidlookup?view=long&pmid=18490403 |issn=}}</ref>
===Long term prognosis===
===Long term prognosis===



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Pneumonia
ICD-9 480

-486

Pneumonia is defined as "inflammation of the lungs."[1]

Classification

Pneumonia can be classified along various dimensions including clinical setting, underlying etiology, and its gross appearance (bronchopneumonia versus lobar pneumonia).

Aspiration pneumonia

Community acquired pneumonia

Atypical pneumonia

Nosocomial pneumonia

Ventilator associated pneumonia

Diagnosis

History and physical examination

A clinical prediction rule found the five following signs from the medical history and physical examination best predicted infiltrates on the chest radiograph of 1134 patients presenting to an emergency room:[2]

  • Temperature > 100 degrees F (37.8 degrees C)
  • Pulse > 100 beats/min
  • Crackles
  • Decreased breath sounds
  • Absence of asthma

The probability of an infiltrate in two separate validations was based on the number of findings:

  • 5 findings - 84% to 91% probability
  • 4 findings - 58% to 85%
  • 3 findings - 35% to 51%
  • 2 findings - 14% to 24%
  • 1 findings - 5% to 9%
  • 0 findings - 2% to 3%

A subsequent study[3] comparing four clinical prediction rules to physician judgment found that two clinical prediction rules, the one above[2] and another[4] were more accurate than physician judgment because of the increased specificity of the prediction rules.

Treatment

Antibiotics

Aspiration pneumonia

Community acquired pneumonia

The optimal duration of antibiotic treatment for community acquired pneumonia is not clear.[5]

Ventilator associated pneumonia

Treatments that are ineffective

Chest physiotherapy includes postural drainage, percussion, and vibration and has been call the 'ketchup-bottle method'[6] of treating pneumonia. Chest physiotherapy and intermittent positive-pressure breathing have been shown not to help in a small randomized controlled trial.[7]

Prognosis

Short term prognosis and the decision to hospitalize

The prognosis of community acquired pneumonia can be estimated with either of three clinical prediction rules:

  • Pneumonia severity index (PSI) - the PSI may be more accurate than the CURB-65[8] and is available online (Pneumonia Severity Index Calculator).
  • CURB-65
  • SMART-COP is a new clinical prediction rule that may be better according to a singel study.[9] Patients are high risk if they have three or more points from the following:
    • systolic blood pressure < 90 (2 points)
    • multilobar chest radiography involvement (1 point)
    • albumin level < 3.5 mg/dl(1 point)
    • high respiratory rate. 25 or more breaths per minute if less than 50 years old, else 30 or more breaths per minute (1 point)
    • tachycardia of 125 or more bpm (1 point)
    • confusion, new onset (1 point)
    • poor oxygenation. Either of the following adds 2 points:
      • PaO2 < 70 mm Hg if less than 50 years old, else < 60 mm Hg
      • PaO2/FiO2 < 333 if less than 50 years old, else if less than 250.
    • arterial pH < 7.35 (2 points)

Prognosis at the time of discharge

Abnormal medical signs at discharge are associated with higher mortality with 30 days.[10]

Long term prognosis

References

  1. Anonymous (2024), Pneumonia (English). Medical Subject Headings. U.S. National Library of Medicine.
  2. 2.0 2.1 Heckerling PS, Tape TG, Wigton RS, et al (1990). "Clinical prediction rule for pulmonary infiltrates". Ann. Intern. Med. 113 (9): 664–70. PMID 2221647[e]
  3. Emerman CL, Dawson N, Speroff T, et al (1991). "Comparison of physician judgment and decision aids for ordering chest radiographs for pneumonia in outpatients". Annals of emergency medicine 20 (11): 1215–9. DOI:10.1016/S0196-0644(05)81474-X. PMID 1952308. Research Blogging.
  4. Gennis P, Gallagher J, Falvo C, Baker S, Than W (1989). "Clinical criteria for the detection of pneumonia in adults: guidelines for ordering chest roentgenograms in the emergency department". The Journal of emergency medicine 7 (3): 263–8. PMID 2745948[e]
  5. Li JZ, Winston LG, Moore DH, Bent S (2007). "Efficacy of short-course antibiotic regimens for community-acquired pneumonia: a meta-analysis". Am. J. Med. 120 (9): 783–90. DOI:10.1016/j.amjmed.2007.04.023. PMID 17765048. Research Blogging.
  6. Murray JF (1979). "The ketchup-bottle method". N. Engl. J. Med. 300 (20): 1155–7. PMID 431639[e]
  7. Graham WG, Bradley DA (1978). "Efficacy of chest physiotherapy and intermittent positive-pressure breathing in the resolution of pneumonia". N. Engl. J. Med. 299 (12): 624–7. PMID 355879[e]
  8. Aujesky D, Auble TE, Yealy DM, et al (2005). "Prospective comparison of three validated prediction rules for prognosis in community-acquired pneumonia". Am. J. Med. 118 (4): 384-92. DOI:10.1016/j.amjmed.2005.01.006. PMID 15808136. Research Blogging.
  9. Charles PG, Wolfe R, Whitby M, et al (August 2008). "SMART-COP: a tool for predicting the need for intensive respiratory or vasopressor support in community-acquired pneumonia". Clin. Infect. Dis. 47 (3): 375–84. DOI:10.1086/589754. PMID 18558884. Research Blogging.
  10. Capelastegui A, España PP, Bilbao A, et al (September 2008). "Pneumonia: criteria for patient instability on hospital discharge". Chest 134 (3): 595–600. DOI:10.1378/chest.07-3039. PMID 18490403. Research Blogging.

External links