Citalopram: Difference between revisions
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===Excretion=== | ===Excretion=== | ||
==Toxicity== | ==Toxicity== | ||
[[Drug toxicity]] includes arrhythmias. The [[United States]] [[Food and Drug Administration]] has issued a warning to not use higher doses because of use of the [[cytochrome P-450]] system and also arrhythmias.<ref>{{cite web |url= http://www.fda.gov/Safety/MedWatch/SafetyInformation/SafetyAlertsforHumanMedicalProducts/ucm297624.htm |title=Safety Alerts for Human Medical Products > Celexa (citalopram hydrobromide) - Drug Safety Communication: Revised Recommendations, Potential Risk of Abnormal Heart Rhythms |author=anonymous |work=fda.gov |year=2012 [last update] |accessdate=March 29, 2012}}</ref> | [[Drug toxicity]] includes arrhythmias. The [[United States of America]] [[Food and Drug Administration]] has issued a warning to not use higher doses because of use of the [[cytochrome P-450]] system and also arrhythmias.<ref>{{cite web |url= http://www.fda.gov/Safety/MedWatch/SafetyInformation/SafetyAlertsforHumanMedicalProducts/ucm297624.htm |title=Safety Alerts for Human Medical Products > Celexa (citalopram hydrobromide) - Drug Safety Communication: Revised Recommendations, Potential Risk of Abnormal Heart Rhythms |author=anonymous |work=fda.gov |year=2012 [last update] |accessdate=March 29, 2012}}</ref> | ||
==External links== | ==External links== | ||
Latest revision as of 10:44, 2 February 2023
In psychiatry, citalopram is a second-generation antidepressant for treating major depressive disorder.
History
Efficacy
Pharmacology
Administration
Distribution
Metabolism
Citalopram is metabolised by cytochrome P-450 CYP3A4 and CYP2C19.
Excretion
Toxicity
Drug toxicity includes arrhythmias. The United States of America Food and Drug Administration has issued a warning to not use higher doses because of use of the cytochrome P-450 system and also arrhythmias.[1]
External links
The most up-to-date information about Citalopram and other drugs can be found at the following sites.
- Citalopram - FDA approved drug information (drug label) from DailyMed (U.S. National Library of Medicine).
- Citalopram - Drug information for consumers from MedlinePlus (U.S. National Library of Medicine).
- Citalopram - Detailed information from DrugBank.
References
- ↑ anonymous (2012 [last update]). Safety Alerts for Human Medical Products > Celexa (citalopram hydrobromide) - Drug Safety Communication: Revised Recommendations, Potential Risk of Abnormal Heart Rhythms. fda.gov. Retrieved on March 29, 2012.