Carbodiimide: Difference between revisions

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imported>David E. Volk
(New page: <noinclude>{{subpages}}</noinclude> {{Chem infobox |align=right |image=center|thumb|250px |width=250px |molname=carbodiimide |synonyms= |molformula= R1-N=C=N-...)
 
imported>David E. Volk
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'''Carbodiimides''' are a type of dehydrating chemical most often used to activate [[carboxylic acid]]s for subsequent coupling with primary [[amines]], producing an amide compound.
'''Carbodiimides''' are a type of dehydrating chemical most often used to activate [[carboxylic acid]]s for subsequent coupling with primary [[amine]]s, producing an [[amide]] compound.  the carboxyl group is often converted to an activated compound by forming an [[NHS-ester]].
 
{{Image|Carbodiimide generic reaction.png|right|500px|Coupling of an amide group to a carboxylic acid activated by a carbodiimide.}}

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Carbodiimide.png
carbodiimide
IUPAC name:
Synonyms:
Formula: R1-N=C=N-R2
 Uses: dehydration reagent
 Properties: activates carboxylates
 Hazards:
Mass (g/mol): CAS #:



Carbodiimides are a type of dehydrating chemical most often used to activate carboxylic acids for subsequent coupling with primary amines, producing an amide compound. the carboxyl group is often converted to an activated compound by forming an NHS-ester.

© Image: David E. Volk
Coupling of an amide group to a carboxylic acid activated by a carbodiimide.
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