Triazole: Difference between revisions
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imported>David E. Volk (New page: {{subpages}} {{Chem infobox |align=right |image=right|thumb|200px |width=200px |molname=triazole |synonyms=1,2,3-triazole;1,2,4-triazole |molformula= C<sub>2</sub...) |
imported>David E. Volk (substituted triazole synthesis equations) |
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The [[triazole]]s are two isomers, namely 1,2,3-triazole or 1,2,4-triazole, with the formula C<sub>2</sub>H<sub>3</sub>N<sub>3</sub>. They are [[aromatic]] ring compounds that are similar to the [[azole]]s [[pyrazole]] and [[imadazole]], but they would have an additional nitrogen atom in the ring structure. Like the azoles, triazoles are used in many antifungal drugs and fungicides, and the triazole-based drugs are more selective for fungi than mammalian cells compared to the azole-based antifungal compounds. | The [[triazole]]s are two isomers, namely 1,2,3-triazole or 1,2,4-triazole, with the formula C<sub>2</sub>H<sub>3</sub>N<sub>3</sub>. They are [[aromatic]] ring compounds that are similar to the [[azole]]s [[pyrazole]] and [[imadazole]], but they would have an additional nitrogen atom in the ring structure. Like the azoles, triazoles are used in many antifungal drugs and fungicides, and the triazole-based drugs are more selective for fungi than mammalian cells compared to the azole-based antifungal compounds. | ||
== Chemistry of substituted 1,2,3-triazoles == | |||
[[Image:1,2,3-triazole synthesis substituted.jpg|right|thumb|300px|Synthesis of substituted 1,2,3-triazoles.]] | |||
Revision as of 10:48, 17 May 2008
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| triazole | |||||||
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| Uses: | antifungal drugs and fungicides | ||||||
| Properties: | basic, azole compound | ||||||
| Hazards: | see side effects & drug interactions | ||||||
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The triazoles are two isomers, namely 1,2,3-triazole or 1,2,4-triazole, with the formula C2H3N3. They are aromatic ring compounds that are similar to the azoles pyrazole and imadazole, but they would have an additional nitrogen atom in the ring structure. Like the azoles, triazoles are used in many antifungal drugs and fungicides, and the triazole-based drugs are more selective for fungi than mammalian cells compared to the azole-based antifungal compounds.
