Poliovirus: Difference between revisions
imported>Cristina Ryoo |
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==Genome structure== | ==Genome structure== | ||
Poliovirus is made up of a RNA genome and a protein capsid. | Poliovirus is made up of a RNA genome and a protein capsid. The genome is a single-strnded positive-sense RNA genome and it is approximately 7500 nucleotides long. The viral component is about 300 Angstrom in diameter with icosahdral symmetry. Polio virus is commonly known as the simplest significant virus because of its short genome and simple composition. | ||
Describe the size and content of the genome. How many chromosomes? Circular or linear? Other interesting features? What is known about its sequence? | Describe the size and content of the genome. How many chromosomes? Circular or linear? Other interesting features? What is known about its sequence? | ||
Does it have any plasmids? Are they important to the organism's lifestyle? | Does it have any plasmids? Are they important to the organism's lifestyle? | ||
==Cell structure and metabolism== | ==Cell structure and metabolism== | ||
Revision as of 14:53, 6 April 2008
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Description and significance
Poliovirus was first isolated by Karl Landersteiner and Erwin Popper in 1909.
Describe the appearance, habitat, etc. of the organism, and why it is important enough to have its genome sequenced. Describe how and where it was isolated. Include a picture or two (with sources) if you can find them.
Genome structure
Poliovirus is made up of a RNA genome and a protein capsid. The genome is a single-strnded positive-sense RNA genome and it is approximately 7500 nucleotides long. The viral component is about 300 Angstrom in diameter with icosahdral symmetry. Polio virus is commonly known as the simplest significant virus because of its short genome and simple composition.
Describe the size and content of the genome. How many chromosomes? Circular or linear? Other interesting features? What is known about its sequence?
Does it have any plasmids? Are they important to the organism's lifestyle?
Cell structure and metabolism
Describe any interesting features and/or cell structures; how it gains energy; what important molecules it produces.
Ecology
Describe any interactions with other organisms (included eukaryotes), contributions to the environment, effect on environment, etc.
Pathology
Poliovirus causes the viral disease, poliomyelitis. Poliomyelitis is an extremely infectious disease. Humans are exclusive, natural host for poliovirus.
How does this organism cause disease? Human, animal, plant hosts? Virulence factors, as well as patient symptoms.
Application to Biotechnology
Does this organism produce any useful compounds or enzymes? What are they and how are they used?
Current Research
References
http://en.wikipedia.org/wiki/Poliovirus
http://www.ncbi.nlm.nih.gov/ICTVdb/ICTVdB/00.052.0.01.001.htm
http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?lvl=0&id=12080
http://www.ncbi.nlm.nih.gov/pubmed/10618373
http://query.nytimes.com/gst/fullpage.html?sec=health&res=9A03E2D81739F933A1575AC0A963948260