Dicloxacillin: Difference between revisions
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imported>David E. Volk m (typos) |
imported>David E. Volk (Chem infobox added) |
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[[Image:Dicloxacillin structure.jpg|right|thumb|250px|{{#ifexist:Template:Dicloxacillin structure.jpg/credit|{{Dicloxacillin structure.jpg/credit}}<br/>|}} | |||
{{Chem infobox | |||
|align=right | |||
|image=[[Image:Dicloxacillin structure.jpg|right|thumb|250px|{{#ifexist:Template:Dicloxacillin structure.jpg/credit|{{Dicloxacillin structure.jpg/credit}}<br/>|}}]] | |||
|width=250px | |||
|molname=dicloxacillin | |||
|synonyms= dichloro oxacillin | |||
|molformula= C<sub>19</sub>H<sub>17</sub>C<sub>l2</sub>N<sub>3</sub>O<sub>5</sub>S | |||
|molmass= 470.3264 | |||
|uses= antibiotic | |||
|properties=beta-lactam | |||
|hazards=see drug interactions | |||
|iupac= see chemistry section | |||
|casnumber=3116-76-5 | |||
}} | |||
'''Dicloxacillin''', (dichloro-[[oxacillin]]) is a beta-lactam based, [[penicillin]]-like, [[penicillinase]]-resistant [[antibiotic]] used to treat infections due to aerobic, Gram-positive and Gram-negative bacteria. For more information about this drug, see the related pages for [[oxacillin]] and [[cloxacillin]]. | '''Dicloxacillin''', (dichloro-[[oxacillin]]) is a beta-lactam based, [[penicillin]]-like, [[penicillinase]]-resistant [[antibiotic]] used to treat infections due to aerobic, Gram-positive and Gram-negative bacteria. For more information about this drug, see the related pages for [[oxacillin]] and [[cloxacillin]]. | ||
== Chemistry == | |||
The IUPAC chemical name of dicloxacillin is (2S,5R,6R)-6-[[3-(2,6-dichlorophenyl)-5-methyl1,2-oxazole-4-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, and it has molecular formula C<sub>19</sub>H<sub>17</sub>C<sub>l2</sub>N<sub>3</sub>O<sub>5</sub>S, giving it a molecular mass of 470.3264 g/mol. It is susceptible to degradation in bacteria that express [[beta-lactamase]]. | |||
== External links == | == External links == | ||
Revision as of 12:12, 3 April 2008
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| dicloxacillin | |||||||
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| Uses: | antibiotic | ||||||
| Properties: | beta-lactam | ||||||
| Hazards: | see drug interactions | ||||||
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Dicloxacillin, (dichloro-oxacillin) is a beta-lactam based, penicillin-like, penicillinase-resistant antibiotic used to treat infections due to aerobic, Gram-positive and Gram-negative bacteria. For more information about this drug, see the related pages for oxacillin and cloxacillin.
Chemistry
The IUPAC chemical name of dicloxacillin is (2S,5R,6R)-6-[[3-(2,6-dichlorophenyl)-5-methyl1,2-oxazole-4-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, and it has molecular formula C19H17Cl2N3O5S, giving it a molecular mass of 470.3264 g/mol. It is susceptible to degradation in bacteria that express beta-lactamase.
External links
- Dicloxacillin - FDA approved drug information (drug label) from DailyMed (U.S. National Library of Medicine).
- Template:MedMaster
- Template:DrugBank