Oseltamivir: Difference between revisions
Jump to navigation
Jump to search
imported>Caesar Schinas m (Bot: Replacing medical templates with CZMed) |
imported>Robert Badgett No edit summary |
||
| Line 16: | Line 16: | ||
}} | }} | ||
'''Oseltamivir''', or '''oseltamivir phosphate''', marketed as '''Tamiflu®''', is an acetamido cyclohexene that is a structural homolog of [[sialic acid]] and it is a [[neuraminidase]] inhibitor. It is used to treat [[ | '''Oseltamivir''', or '''oseltamivir phosphate''', marketed as '''Tamiflu®''', is an acetamido cyclohexene that is a structural homolog of [[sialic acid]] and it is a [[neuraminidase]] inhibitor. It is used to treat [[influenza]] A and B infection and also is used prophylactically. The active form is the ester hydrolysed form, a carboxylate. Oseltamivir (like [[zanamivir]]) acts as a transition-state analogue inhibitor of influenza neuraminidase. | ||
== Chemistry == | == Chemistry == | ||
Revision as of 15:25, 22 December 2012
|
| |||||||
| oseltamivir | |||||||
| |||||||
| Uses: | influenza A & B | ||||||
| Properties: | sialic acid homolog, neuraminidase inhibitor | ||||||
| Hazards: | see drug interactions | ||||||
| |||||||
Oseltamivir, or oseltamivir phosphate, marketed as Tamiflu®, is an acetamido cyclohexene that is a structural homolog of sialic acid and it is a neuraminidase inhibitor. It is used to treat influenza A and B infection and also is used prophylactically. The active form is the ester hydrolysed form, a carboxylate. Oseltamivir (like zanamivir) acts as a transition-state analogue inhibitor of influenza neuraminidase.
Chemistry
Its IUPAC chemical name is ethyl (3R,4R,5S)-4-acetamido-5-amino-3-pentan-3-yloxycyclohexene-1-carboxylate and its chemical formula is C16H28N2O4, giving it a molecular mass of 312.4045 g/mol.
External links
The most up-to-date information about Oseltamivir and other drugs can be found at the following sites.
- Oseltamivir - FDA approved drug information (drug label) from DailyMed (U.S. National Library of Medicine).
- Oseltamivir - Drug information for consumers from MedlinePlus (U.S. National Library of Medicine).
- Oseltamivir - Detailed information from DrugBank.