imported>David E. Volk |
imported>David E. Volk |
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| [[Image:Tyrosine stick figure.jpg|right|thumb|150px|{{#ifexist:Template:Tyrosine stick figure.jpg/credit|{{Tyrosine stick figure.jpg/credit}}<br/>|}}'''Tyrosine''', a common amino acid.]]
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| '''Tyrosine''', abbreviated '''Tyr''' or '''Y''', is one of the twenty common <math>\alpha</math>-[[amino acid]]s used by living organisms to build [[protein]]s. It is one of the four [[aromatic]] amino acids together with [[histidine]], [[phenylalanine]] and [[tryptophan]]. It is one of three amino acids subject to [[phosphorylation]] by tyrosine [[kinase]]s due to the presence of a hydroxyl group, (-OH). Such phosphorylation events are central to many [[cell-signalling]] pathways. Although tyrosine is [[hydrophobic]] and the side chain is mostly buried in proteins, it is often situated such that the hydroxy group is accessible.
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