Ampicillin

(CC) Image: David E. Volk
ampicillin
IUPAC name: see chemistry section Synonyms: aminobenzylpenicillin Formula: C16H19N3O4S
Uses:	antibiotic drug
Properties:	beta-lactam
Hazards:	see drug interactions
Mass (g/mol): CAS #: 349.4048 69-53-4

Ampicillin, or aminobenzylpenicillin, is a broad spectrum antibiotic and a derivative of penicillin. It is used to treat infections of E. coli, P. mirabilis, enterococci, Shigella, S. typhosa and other Salmonella, nonpenicillinase-producing N. gononhoeae, H. influenzae, staphylococci, and streptococci including streptoc. It is also widely used in molecular biology labs during the over-expression of proteins in bacterial cells that are tolerant of ampicillin. This ensures that only the bacteria of interest grow in the media and produce the protein of interest.

Ampicillin is a penicillin beta-lactam antibiotic used to eliminate susceptible, usually Gram-positive, organisms. Like penicillin, ampicillin inhibits the last stage of bacterial cell wall synthesis by binding to specific penicillin-binding proteins in the bacterial cell wall.

Its IUPAC chemical name is (2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid and it has chemical formula C₁₆H₁₉N₃O₄S, giving it a molecular mass of 349.4048 g/mol.

Synonyms of ampicillin

Ampicilline Ampicillinum Ampicilline Ampicillina Ampicillin Ampicillin Trihydrate Ampicillin Sodium Ampicillin Base

Ampicillin Anhydrous Ampicillin Anhydrate Ampicillin Acid Ampicilina Anhydrous Ampicillin Bayer 5427 D-Ampicillin Aminobenzylpenicillin

Brand names of ampicillin

AB-PC® Ab-Pc Sol® Acillin® Adobacillin® Alpen® Amblosin® Amcill® Amfipen® Amfipen V® Amipenix S® Ampen® Ampi® Ampi-Bol® Ampi-Co® Ampi-Tab® Ampichel® Ampicil® Ampicillin A® Ampicin® Ampifarm® Ampikel® Ampimed® Ampipenin® Ampipenin, Nt3® Ampiscel® Ampisyn® Ampivax® Ampivet® Amplacilina®

Amplin® Amplipenyl® Amplisom® Amplital® Ampy-Penyl® Austrapen® BRL® Binotal® Bonapicillin® Britacil® Campicillin® Cimex® Copharcilin® D-Cillin® Delcillin® Deripen® Divercillin® Doktacillin® Duphacillin® Geocillin® Grampenil® Guicitrina® Guicitrine® Lifeampil® Morepen® Norobrittin® Novo-Ampicillin® Nuvapen®

Olin Kid® Omnipen® Omnipen-N® Orbicilina® Pen A® Pen Ampil® Pen a Oral® Penbristol® Penbritin® Penbritin Paediatric® Penbritin Syrup® Penbritin-S® Penbrock® Penicline® Penimic® Pensyn® Pentrex® Pentrexl® Pentrexyl® Pfizerpen A® Pfizerpen-A® Polycillin® Polycillin-N® Ponecil® Princillin® Principen® Principen '125'® Principen '250'®

Principen '500'® Qidamp® Racenacillin® Ro-Ampen® Rosampline® Roscillin® Semicillin® Semicillin R® Servicillin® Sk-Ampicillin® Spectrobid® Sumipanto® Supen® Synpenin® Texcillin® Tokiocillin® Tolomol® Totacillin® Totacillin-N® Totalciclina® Totapen® Trifacilina® Ultrabion® Ultrabron® Vampen® Viccillin® Viccillin S® Wypicil®

External links

The most up-to-date information about Ampicillin and other drugs can be found at the following sites.

• Ampicillin - FDA approved drug information (drug label) from DailyMed (U.S. National Library of Medicine).
• Ampicillin - Drug information for consumers from MedlinePlus (U.S. National Library of Medicine).
• Ampicillin - Detailed information from DrugBank.